Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 24.55
Human Site: S507 Identified Species: 36
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S507 T S P E T S R S S D A F T T Q
Chimpanzee Pan troglodytes XP_518055 1227 139177 S507 T S P E T S R S S D A F T T Q
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S507 T S P E T N R S S D T F T T Q
Dog Lupus familis XP_549061 1234 139874 S508 T S P E T S R S S D A F T T Q
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S508 S S P D T S R S S D V F S T Q
Rat Rattus norvegicus Q7M6Z5 1394 158861 H520 M A Q E S K G H A V S L K E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S513 T G Q V T K R S S D D F T T Q
Frog Xenopus laevis Q91784 1226 138905 S510 E D S G E K R S S D G F T T N
Zebra Danio Brachydanio rerio Q58G59 1363 154819 T611 S S S Y S E Q T Q W D G T H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 V182 V R E R G S G V Y V P N L H A
Honey Bee Apis mellifera XP_395595 1064 123475 D456 V L Y L K I L D I Q N D Q K K
Nematode Worm Caenorhab. elegans P46873 699 78760 M97 G S G K T F S M Q G I E T I P
Sea Urchin Strong. purpuratus P46872 699 78679 G97 N G T I F A Y G Q T G T G K T
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 A438 R I A W L E A A N E D L C R E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 R512 D S Y D V G P R S N N V L F P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 R326 S T L R F G M R A K S I K N K
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 86.6 100 N.A. 73.3 6.6 N.A. N.A. 66.6 46.6 13.3 N.A. 6.6 0 20 0
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 33.3 N.A. N.A. 66.6 46.6 40 N.A. 6.6 6.6 26.6 6.6
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 0 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 26.6 N.A. N.A. 26.6 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 7 7 7 13 0 19 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 7 7 0 13 0 0 0 7 0 44 19 7 0 0 0 % D
% Glu: 7 0 7 32 7 13 0 0 0 7 0 7 0 7 7 % E
% Phe: 0 0 0 0 13 7 0 0 0 0 0 44 0 7 0 % F
% Gly: 7 13 7 7 7 13 13 7 0 7 13 7 7 0 7 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 13 0 % H
% Ile: 0 7 0 7 0 7 0 0 7 0 7 7 0 7 0 % I
% Lys: 0 0 0 7 7 19 0 0 0 7 0 0 13 13 13 % K
% Leu: 0 7 7 7 7 0 7 0 0 0 0 13 13 0 0 % L
% Met: 7 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 7 0 0 7 7 13 7 0 7 7 % N
% Pro: 0 0 32 0 0 0 7 0 0 0 7 0 0 0 13 % P
% Gln: 0 0 13 0 0 0 7 0 19 7 0 0 7 0 38 % Q
% Arg: 7 7 0 13 0 0 44 13 0 0 0 0 0 7 0 % R
% Ser: 19 50 13 0 13 32 7 44 50 0 13 0 7 0 0 % S
% Thr: 32 7 7 0 44 0 0 7 0 7 7 7 50 44 7 % T
% Val: 13 0 0 7 7 0 0 7 0 13 7 7 0 0 0 % V
% Trp: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 13 7 0 0 7 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _